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Is Acetaldehyde the cause of hangovers?

Everybody knows acetaldehyde, the byproduct that is created when our body breaks down ethanol, has a close relationship with hangover symptoms. But acetaldehyde is not the ONLY thing that contributes to a hangover. We took a deeper dive to figure out what the root cause is. According to Johns Hopkins Medical Center, alcohol intoxicates the brain, the liver,  the heart, the blood vessels, the kidneys, the lining of the stomach, and various hormonal and regulatory systems. Even the word “intoxicated” indicates alcohol’s true nature: a toxic substance. When toxic substances are introduced to our body, our body triggers the defense mechanism called "inflammation". Per Ceders-Sinai Hospital researchers in Los Angeles, this minor inflammatory response can cause a host of various hangover symptoms such as headache, fatigue, nausea, stomach upset, and many more. Alcohol also acts as a depressant to the CNS (Central Nervous System), so it slows down the chemicals and pathways that your brain cells use to send signals to our body. These disruptions can change mood, behavior, movement coordination, and logical thinking. (1

 

Key to Hangover Remedy

Understanding that alcohol affects the entire body - not just one targeted area- is critical. And therefore it is equally important to note that in order to efficiently release toxicity of alcohol out of your body, you need various components that help the hangover recovery process. This is why Iluna is a great hangover cure product because we are not relying on one or two key ingredients to relieve the hangover symptoms. Iluna contains all the necessary ingredients that help with the hangover recovery process in every level. When the medicinal herbs are formulated correctly, the herbs work synergistically which is also known as the "entourage effect" - minus THC and CBD as we do not contain any cannabis or hemp in our formula. Not only does Iluna's proprietary formula apply powerful ingredients that boost the immune system, but also it enhances the functionality of the brain, the liver, the heart, the kidneys, and the stomach. Let’s take a deeper dive and see how this all works together. 

Iluna contains 14 different medical-grade, medicinal herbs that aid quick and efficient hangover recovery. 

 

When alcohol is absorbed into the body, it races to your brain acting as a depressant to the CNS (Central Nervous System) to slow down the chemicals and pathways that the brain cells use to send messages to the body. This disruptions can change person’s mood and behaviors. (1)

 Best Hangover Remedy Herb List | Iluna

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The List of Herbs For Hangover Remedy

Daidzin from Kudzu root has an awakening effect that can help you think clearly by working as a neuroglia cell deactivator (brain writing the message to our organs), and help maintain homeostasis while intoxicated. (2)

Curumin from Turmeric tuber will strengthen the CNS (central nervous system) so it helps the brain to send clear signals to your body system. (3)

Geniposide and genipin from Gardenia fruit help ease depression and anxiety. They also promote resistance to depression- and anxiety like behaviors.(4) 

Gomisin A from GoJi berry calms and protects the brain from stress by repression of death of neurons and increasing striatum & hypothalamus dopamine. (5)

Your liver, the main filter of our body, detoxifies and removes alcohol from the blood through a process known as oxidation. Once the liver finishes the process, alcohol becomes water and carbon dioxide. If alcohol accumulates in the system for a longer period of time, it will start the inflammation process to our body. Silymarin from Amomum villosum and milk thistle, which is a strong antioxidant that has fat soluble character which helps attach the cell wall to protect cells from lipid peroxidation. (6)

Schizandrin, Gomisin A & N from five-flavor berry and glycyrrhizin, glycyrrhizin acid, and liquiritigenin from licorice root protects liver by repression of death of hepatocytes and  working as inhibitor of HSC (Hepatic Stellate Cell: cell that can cause Liver fibrosis).(7)(8) Also rutaecarpine protects the liver from cirrhosis by controlling enzyme levels in the blood and repressing RNA & protein expression. (9) Betaine from Goji berry functions as "methyl donors" which stops liver damage and heals damaged liver. (10) 

Drinking alcohol affects cardiovascular as well. (11) Alcohol sometimes works as a vasodilator, causing blood vessels to relax and expand. However at some high levels, alcohol may work as a vasoconstrictor, causing veins to tighten and constrict. Evodiamine and rutaecarpine from Evodia fruit, Scoparone from Artemisia capillaris and chlorogenic acid from Gardenia fruit help regulate proper blood circulation by controlling the level of expansion and constriction of the blood vessels, and also reduces the size of myocardial infarction. (9)(13)(14) And goshyuamide II from Evodia fruit and betaine from Goji berry prevent blood platelets from coagulating (blood clots). Betaine also works as a homocysteine inhibitor that protects from shear stress which can cause deformation of blood vessels and regulate blood circulation. (5)(9) These compounds will help ease your dizziness, weakness, and fatigue.

Kidneys also work as filters for toxic substances. Alcohol weakens the function of kidneys which hinders kidneys from filtering the blood (high blood pressure). This doesn’t necessarily mean that you have a bloody toilet. Have you ever noticed you are going to the bathroom a lot more often than when you are not drinking? You might think it's because you have been drinking a lot of fluids, but that is not true. Usually the brain creates a hormone that keeps your kidney from making too much urine. However when alcohol is introduced to the body, the brain does not interfere as much. This may cause dehydration as you will have to go to the bathroom more frequently. Alcohol also affects the ability to regulate fluid and electrolytes in the body. When alcohol dehydrates the body, the drying effect can affect the normal function of cells and organs. (15)

Loganin from Cornus fruits is one of key compounds when it comes to nephropathy as it reduces the levels of CTGF (Connective Tissue Growth Factor- plays a pathogenic role in nephropathy.(16)(17) In Traditional Eastern Medicine, Cornus fruits is one of the most commonly used herbs to regulate urine, restore/promote kidney functionality, and balance renal hormones (kidney hormone).

Alcohol can wear down the lining of the stomach and increases the production of stomach acid, which can contribute to ulcers.(18) Alcohol may also alter nutrient breakdown, absorption, transportation, storage, and excretion, leading to nutrient deficiencies and/or trouble fully using nutrients. (19) This can cause bloating, heartburn, nausea, vomiting, and diarrhea. To overcome digestive system related hangover symptoms, Iluna contains honey for bloating and heartburn, ginger and cinnamon twigs for nausea and vomiting, plus awesome anti-inflammatory and anti-allergy herbs such as Evodia fruit, five-flavor berry, Turmeric tuber, Artemisia capillaris, and Licorice root to cover symptoms like diarrhea and aches in your body including headache. (3)(7)(8)(9)(13)

 best hangover cure iluna recovery

Our Goal

We're here to help you enjoy and maintain wellness.

Iluna's proprietary formulation is based on Traditional Eastern Medicine which is why we are the experts when it comes to medicinal herbs. A recent study notes moderate alcohol consumption can be beneficial to well-being. Our goal is to help you enjoy your moments without having to worry about hangovers. Be out there and be confident! Enjoy more and worry less with Iluna. 

Check out Iluna here.

 100% Natural | Vegan | No Chemicals | No Preservatives | No Sugar
Outsmart Your Morning.

 

References:
(1) https://www.niaaa.nih.gov/alcohols-effects-health/alcohols-effects-body (2) https://bit.ly/2WlDqps (3) https://bit.ly/2Ce6GaO (4) Boominathan, L.(2017), Genome-2-Bio-Medicine Discovery center Natural product-based therapy for anxiety and depression. (5) https://bit.ly/3j5xlXW (6) https://bit.ly/32iBJNm (7) https://bit.ly/3fsUZvz (8) https://bit.ly/2OqT5zq (9) https://bit.ly/2WiBFtj (10) ncbi.nlm.nih.gov/pubmed/26850693 (11) WHO (2018), global status report on alcohol and health p73-74 (12) Piano MR. (2017), Alcohol’s effects on the Cardiovascular system. Alcohol Res. 39(2):219-241 (13) https://bit.ly/2CDSQhK  (14) https://bit.ly/32flWis (15) www.kidney.org/news/kidneyCare/winter10/AlcoholAffects (16) https://bit.ly/38STx34 (17) https://pubmed.ncbi.nlm.nih.gov/21978885 (18) Mayo Clinic (2018) Peptic Ulcer (19) National Institute on Alcohol Abuse and Alcoholism (1993). Alcohol and Nutrition